Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440854 | 0.83 | ATM (0.33) | ALDH1A1TSHRALOX15ATMNPSR1 | |
| SCHEMBL10651517 | 0.81 | — | — | |
| SCHEMBL2113072 | 0.81 | MEN1 (0.38) | TSHRATMNPSR1MEN1KMT2A | |
| SCHEMBL19847299 | 0.79 | TSHR (0.54) | L3MBTL1ALDH1A1TSHRALOX15ATM | |
| SCHEMBL3120720 | 0.79 | HCAR2 (0.54) | L3MBTL1ALDH1A1TSHRALOX15ATM | |
| SCHEMBL10655043 | 0.77 | TSHR (0.40) | L3MBTL1ALDH1A1TSHRALOX15ATM | |
| SCHEMBL27525497 | 0.77 | TSHR (0.40) | L3MBTL1ALDH1A1TSHRALOX15ATM | |
| SCHEMBL15482569 | 0.77 | TSHR (0.40) | L3MBTL1ALDH1A1TSHRALOX15ATM | |
| SCHEMBL15482568 | 0.77 | SMN1; SMN2 (0.40) | L3MBTL1ALDH1A1TSHRALOX15ATM | |
| SCHEMBL4674171 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132814-A1 | Ester derivative of substituted acetic acid and preparing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-02-13 | — | — | EP | disclosed |
| EP-0103265-A2 | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1984-03-21 | — | — | EP | disclosed |