Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.53 |
| ▸ | RAB9A | P51151 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 11/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16471213 | 0.76 | KDM4E (0.39) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL8300771 | 0.76 | NPC1 (0.55) | NPC1KMT2ARAB9AMEN1KDM4E | |
| SCHEMBL416916 | 0.75 | KDM4E (0.61) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL8995917 | 0.74 | KDM4E (0.67) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL10759780 | 0.74 | NPC1 (0.81) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL10772265 | 0.74 | NPC1 (0.81) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL17678276 | 0.74 | NPC1 (0.43) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL720834 | 0.74 | NPC1 (0.43) | NPC1KMT2ARAB9AMEN1MAPT | |
| Ammonia Solution, Strong SCHEMBL3507660 | 0.73 | KDM4E (0.58) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL7047234 | 0.71 | MEN1 (0.79) | NPC1KMT2ARAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134471-A1 | Azo dyestuffs and liquid-crystal materials containing these dyestuffs | BASF Aktiengesellschaft (DE) | 1985-03-20 | — | — | EP | disclosed |