Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | APP | P05067 | 2/20 | 0.74 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015020 | 0.90 | TP53 (0.81) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL13291441 | 0.89 | MAPT (0.80) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL11011184 | 0.88 | TP53 (0.78) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL772566 | 0.88 | MAPT (0.78) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| Bromide SCHEMBL3867312 | 0.88 | MAPT (0.78) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL11008472 | 0.88 | MAPT (0.78) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL13290939 | 0.88 | MAPT (0.78) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL13394267 | 0.88 | MAPT (0.78) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL3045412 | 0.88 | MAPT (0.78) | TP53MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL13394273 | 0.85 | MAPT (0.74) | TP53MAPTLMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |