Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979797 | 0.82 | MAPT (0.46) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL10978657 | 0.81 | NOX1 (0.46) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL69897 | 0.76 | CA1 (0.55) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9508150 | 0.76 | CA1 (0.55) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11100052 | 0.75 | NOX1 (0.40) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL2880869 | 0.75 | PTPRC (0.49) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5193420 | 0.73 | PTPRC (0.48) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11015056 | 0.73 | NOX1 (0.39) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9295482 | 0.73 | PTPRC (0.62) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL2330668 | 0.73 | PLAU (0.61) | MAPTKDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536507-A | ANTIASTHMA AGENTS | MERCK & CO., INC. (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0052912-A1 | 7-Fluoro-dibenzo(b,f)thiepin derivatives, their preparation and resolution, and compositions containing them | MERCK & CO. INC. (US) | 1982-06-02 | — | — | EP | disclosed |