Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729711 | 0.79 | CYP1A2 (0.37) | MAPTLMNAPOLBHTTRECQL | |
| SCHEMBL18977949 | 0.73 | IDO1 (0.69) | L3MBTL1IDO1MAPTLMNAGAA | |
| SCHEMBL17321749 | 0.69 | IDO1 (0.64) | L3MBTL1IDO1MAPTLMNAGAA | |
| SCHEMBL17321751 | 0.69 | IDO1 (0.64) | L3MBTL1IDO1MAPTLMNAGAA | |
| SCHEMBL17321590 | 0.67 | IDO1 (0.56) | L3MBTL1IDO1MAPTLMNAGAA | |
| SCHEMBL30816757 | 0.65 | IDO1 (0.69) | L3MBTL1IDO1MAPTLMNAGAA | |
| SCHEMBL30816758 | 0.65 | IDO1 (0.69) | L3MBTL1IDO1MAPTLMNAGAA | |
| SCHEMBL17321659 | 0.64 | IDO1 (0.51) | L3MBTL1IDO1MAPTLMNAGAA | |
| SCHEMBL17321750 | 0.63 | IDO1 (0.55) | L3MBTL1IDO1MAPTLMNAGAA | |
| SCHEMBL17321756 | 0.62 | IDO1 (0.53) | L3MBTL1IDO1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157656-A2 | Process and intermediates for the preparation of aryl substituded pyrido [1,4] benzodiazepines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1985-10-09 | — | — | EP | disclosed |