Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.54 |
| ▸ | ANPEP | P15144 | 4/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018019 | 0.88 | DPP4 (0.55) | DPP4ANPEPNR1H2NR1H3ESR1 | |
| SCHEMBL11017723 | 0.88 | DPP4 (0.55) | DPP4ANPEPNR1H2NR1H3ESR1 | |
| SCHEMBL11020351 | 0.87 | ANPEP (0.51) | DPP4ANPEPNR1H2NR1H3ESR1 | |
| SCHEMBL11018523 | 0.84 | DPP4 (0.58) | DPP4ANPEPNR1H2NR1H3HPGD | |
| SCHEMBL11019792 | 0.84 | ANPEP (0.46) | DPP4ANPEPNR1H2NR1H3NPSR1 | |
| SCHEMBL11018284 | 0.82 | DPP4 (0.48) | DPP4ANPEPNR1H2NR1H3ELANE | |
| SCHEMBL11020066 | 0.82 | DPP4 (0.64) | DPP4ANPEPNR1H2NR1H3PTK2B | |
| SCHEMBL11020819 | 0.82 | DPP4 (0.50) | DPP4ANPEPNR1H2NR1H3HPGD | |
| SCHEMBL11019951 | 0.81 | DPP4 (0.52) | DPP4ANPEPNR1H2NR1H3NPSR1 | |
| SCHEMBL11017998 | 0.81 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |