Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.53 |
| ▸ | ANPEP | P15144 | 4/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021587 | 0.87 | ANPEP (0.48) | DPP4ANPEPKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11018073 | 0.87 | DPP4 (0.60) | DPP4ANPEPNR1H2NR1H3MEN1 | |
| SCHEMBL11021403 | 0.84 | DPP4 (0.49) | DPP4ANPEPNR1H2NR1H3KMT2A | |
| SCHEMBL11019207 | 0.84 | DPP4 (0.58) | DPP4ANPEPNR1H2NR1H3MEN1 | |
| SCHEMBL11021398 | 0.83 | DPP4 (0.57) | DPP4ANPEPNR1H2NR1H3MEN1 | |
| SCHEMBL11018520 | 0.83 | DPP4 (0.57) | DPP4ANPEPNR1H2NR1H3MEN1 | |
| SCHEMBL11021646 | 0.82 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3MEN1 | |
| SCHEMBL11017174 | 0.82 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3MEN1 | |
| SCHEMBL11020289 | 0.82 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3MEN1 | |
| SCHEMBL11018022 | 0.81 | DPP4 (0.53) | DPP4ANPEPNR1H2NR1H3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |