Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021434 | 1.00 | TP53 (0.61) | TP53MAPK1RAB9AHTR7LMNA | |
| SCHEMBL11019543 | 1.00 | TP53 (0.61) | TP53MAPK1RAB9AHTR7LMNA | |
| SCHEMBL11021168 | 1.00 | TP53 (0.61) | TP53MAPK1RAB9AHTR7LMNA | |
| SCHEMBL11019866 | 1.00 | TP53 (0.61) | TP53MAPK1RAB9AHTR7LMNA | |
| SCHEMBL10525200 | 1.00 | TP53 (0.61) | TP53MAPK1RAB9AHTR7LMNA | |
| SCHEMBL11021406 | 1.00 | TP53 (0.61) | TP53MAPK1RAB9AHTR7LMNA | |
| SCHEMBL11019954 | 1.00 | TP53 (0.61) | TP53MAPK1RAB9AHTR7LMNA | |
| SCHEMBL9482701 | 0.98 | TP53 (0.62) | TP53MAPK1RAB9AHTR7LMNA | |
| SCHEMBL11020791 | 0.96 | TP53 (0.57) | TP53MAPK1RAB9AHTR7LMNA | |
| SCHEMBL11023081 | 0.92 | TP53 (0.65) | TP53MAPK1RAB9AHTR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |