Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.55 |
| ▸ | ANPEP | P15144 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TYK2 | P29597 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018033 | 0.90 | DPP4 (0.58) | DPP4ANPEPNR1H2NR1H3KMT2A | |
| SCHEMBL11021588 | 0.89 | DPP4 (0.52) | DPP4ANPEPALDH1A1NR1H2NR1H3 | |
| SCHEMBL11020138 | 0.88 | DPP4 (0.56) | DPP4ANPEPALDH1A1NR1H2NR1H3 | |
| SCHEMBL11016999 | 0.86 | DPP4 (0.56) | DPP4ANPEPALDH1A1NR1H2NR1H3 | |
| SCHEMBL11017807 | 0.84 | DPP4 (0.52) | DPP4ANPEPNR1H2NR1H3KMT2A | |
| SCHEMBL11021459 | 0.84 | DPP4 (0.52) | DPP4ANPEPALDH1A1NR1H2NR1H3 | |
| SCHEMBL11021393 | 0.83 | ABCB1 (0.52) | DPP4ANPEPALDH1A1KMT2AMEN1 | |
| SCHEMBL11018238 | 0.83 | DPP4 (0.51) | DPP4ANPEPALDH1A1NR1H2NR1H3 | |
| SCHEMBL11020213 | 0.83 | DPP4 (0.53) | DPP4ANPEPALDH1A1NR1H2NR1H3 | |
| SCHEMBL11017926 | 0.83 | DPP4 (0.64) | DPP4ANPEPNR1H2NR1H3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059388-B1 | IMIDAZODIAZEPINES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-05-29 | — | — | EP | claimed |
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |