Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.54 |
| ▸ | ANPEP | P15144 | 5/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018546 | 0.95 | DPP4 (0.57) | DPP4ANPEPKEAP1NR1H2NR1H3 | |
| SCHEMBL11021915 | 0.87 | DPP4 (0.56) | DPP4ANPEPKEAP1NR1H2NR1H3 | |
| SCHEMBL11019233 | 0.82 | DPP4 (0.55) | DPP4ANPEPKEAP1NR1H2NR1H3 | |
| SCHEMBL11021933 | 0.82 | DPP4 (0.55) | DPP4ANPEPKEAP1NR1H2NR1H3 | |
| SCHEMBL11018662 | 0.80 | DPP4 (0.58) | DPP4ANPEPKEAP1NR1H2NR1H3 | |
| SCHEMBL11018282 | 0.80 | DPP4 (0.61) | DPP4ANPEPKEAP1NR1H2NR1H3 | |
| SCHEMBL11020758 | 0.79 | DPP4 (0.60) | DPP4ANPEPKEAP1NR1H2NR1H3 | |
| SCHEMBL11018518 | 0.78 | DPP4 (0.56) | DPP4ANPEPKEAP1NR1H2NR1H3 | |
| SCHEMBL11020637 | 0.78 | DPP4 (0.58) | DPP4ANPEPKEAP1NR1H2NR1H3 | |
| SCHEMBL10878219 | 0.78 | DPP4 (0.68) | DPP4ANPEPNR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |