Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.55 |
| ▸ | ANPEP | P15144 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020066 | 0.93 | DPP4 (0.64) | DPP4ANPEPPOLBHTTKDM4E | |
| SCHEMBL11019249 | 0.88 | DPP4 (0.55) | DPP4ANPEPALDH1A1NR1H2NR1H3 | |
| SCHEMBL11017325 | 0.87 | DPP4 (0.54) | DPP4ANPEPALDH1A1NR1H2NR1H3 | |
| SCHEMBL11022208 | 0.87 | DPP4 (0.59) | DPP4ANPEPALDH1A1NR1H2NR1H3 | |
| SCHEMBL11020653 | 0.86 | DPP4 (0.53) | DPP4ANPEPPOLBHTTKDM4E | |
| SCHEMBL11016792 | 0.86 | DPP4 (0.55) | DPP4ANPEPALDH1A1HPGDNR1H2 | |
| SCHEMBL11020131 | 0.86 | DPP4 (0.57) | DPP4ANPEPNR1H2NR1H3TYMS | |
| SCHEMBL11018644 | 0.86 | DPP4 (0.57) | DPP4ANPEPNR1H2NR1H3TYMS | |
| SCHEMBL11017664 | 0.84 | ANPEP (0.52) | DPP4ANPEPPOLBHTTALDH1A1 | |
| SCHEMBL11019712 | 0.84 | ANPEP (0.52) | DPP4ANPEPPOLBHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |