Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.52 |
| ▸ | ANPEP | P15144 | 4/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018848 | 0.86 | DPP4 (0.55) | DPP4ANPEPNR1H2NR1H3NPC1 | |
| SCHEMBL11020066 | 0.80 | DPP4 (0.64) | DPP4ANPEPNR1H2NR1H3NPC1 | |
| SCHEMBL11017735 | 0.79 | DPP4 (0.60) | DPP4ANPEPNR1H2NR1H3NPC1 | |
| SCHEMBL11021697 | 0.79 | MEN1 (0.53) | DPP4ANPEPMEN1KMT2AALDH1A1 | |
| SCHEMBL11018073 | 0.77 | DPP4 (0.60) | DPP4ANPEPNR1H2NR1H3NPC1 | |
| SCHEMBL11019780 | 0.77 | DPP4 (0.62) | DPP4ANPEPNR1H2NR1H3MEN1 | |
| SCHEMBL11019031 | 0.77 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3NPC1 | |
| SCHEMBL11018523 | 0.76 | DPP4 (0.58) | DPP4ANPEPNR1H2NR1H3NPC1 | |
| SCHEMBL11019207 | 0.76 | DPP4 (0.58) | DPP4ANPEPNR1H2NR1H3NPC1 | |
| SCHEMBL10878219 | 0.76 | DPP4 (0.68) | DPP4ANPEPNR1H2NR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |