SCHEMBL11019593

SCHEMBL11019593

CO[Si](C)(CCCOC[C@H]1CO1)OC

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.58
ALDH1A1 P00352 5/20 0.55
TDP1 Q9NUW8 1/20 0.55
MAPK1 P28482 1/20 0.41
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28064 1.00 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL18101818 1.00 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
Phosphine SCHEMBL22165491 0.98 TSHR (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL29223191 0.96 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL187760 0.96 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL5605557 0.95 TSHR (0.64) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3788765 0.93 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL23706448 0.93 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL23706443 0.93 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL23706409 0.93 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0159715-A2 Novel polymer and cured product of the same Kanegafuchi Chemical Industry Co., Ltd. (JP) 1985-10-30 EP disclosed