Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021551 | 0.93 | MEN1 (0.77) | MEN1KMT2AKDM4ERXFP1CYP1A1 | |
| SCHEMBL11023288 | 0.84 | MEN1 (0.64) | MEN1KMT2AKDM4ERXFP1CYP1A1 | |
| SCHEMBL5480537 | 0.82 | KDM4E (0.69) | MEN1KMT2AKDM4ERXFP1HPGD | |
| SCHEMBL11019911 | 0.81 | MEN1 (0.82) | MEN1KMT2AKDM4ERXFP1HPGD | |
| SCHEMBL11022369 | 0.81 | MEN1 (0.72) | MEN1KMT2AKDM4ERXFP1HPGD | |
| SCHEMBL11024447 | 0.81 | MEN1 (0.83) | MEN1KMT2AKDM4ERXFP1HPGD | |
| SCHEMBL11019113 | 0.81 | MEN1 (0.71) | MEN1KMT2AKDM4ERXFP1CYP1A1 | |
| SCHEMBL11021916 | 0.80 | KDM4E (0.49) | MEN1KMT2AKDM4ERXFP1HPGD | |
| SCHEMBL11017682 | 0.80 | MEN1 (0.81) | MEN1KMT2AKDM4ERXFP1CYP1A1 | |
| SCHEMBL11018819 | 0.79 | KDM4E (0.59) | MEN1KMT2AKDM4ERXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |