Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018673 | 1.00 | TRPV1 (0.41) | TRPV1ACHEMAOBPTPN1BACE1 | |
| SCHEMBL11022021 | 1.00 | TRPV1 (0.41) | TRPV1ACHEMAOBPTPN1BACE1 | |
| SCHEMBL11019787 | 1.00 | TRPV1 (0.41) | TRPV1ACHEMAOBPTPN1BACE1 | |
| SCHEMBL11019790 | 1.00 | TRPV1 (0.41) | TRPV1ACHEMAOBPTPN1BACE1 | |
| SCHEMBL11018670 | 1.00 | TRPV1 (0.41) | TRPV1ACHEMAOBPTPN1BACE1 | |
| SCHEMBL11020687 | 1.00 | TRPV1 (0.41) | TRPV1ACHEMAOBPTPN1BACE1 | |
| SCHEMBL11020690 | 1.00 | TRPV1 (0.41) | TRPV1ACHEMAOBPTPN1BACE1 | |
| SCHEMBL11022023 | 1.00 | TRPV1 (0.41) | TRPV1ACHEMAOBPTPN1BACE1 | |
| SCHEMBL11022643 | 0.98 | TRPV1 (0.43) | TRPV1MAPTKDM4ETDP1ADRB2 | |
| SCHEMBL11022644 | 0.98 | TRPV1 (0.43) | TRPV1MAPTKDM4ETDP1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4522759-A | ANTIALLERGENS | EISAI CO., LTD. (JP) | 1985-06-11 | — | — | US | disclosed |
| EP-0091694-A1 | Polyprenylcarboxylic acid amides and process for preparing the same | Eisai Co., Ltd. (JP) | 1983-10-19 | — | — | EP | disclosed |