Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.58 |
| ▸ | DHODH | Q02127 | 14/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11431885 | 0.93 | TYMP (0.56) | TYMPDHODHJAK2THRB | |
| SCHEMBL11760504 | 0.88 | DHODH (0.56) | TYMPDHODHJAK2THRB | |
| SCHEMBL11164274 | 0.82 | NSD2 (0.51) | DHODHJAK2THRB | |
| SCHEMBL11762589 | 0.80 | DHODH (0.55) | DHODHJAK2THRB | |
| SCHEMBL11431884 | 0.80 | TYMP (0.60) | TYMPDHODH | |
| SCHEMBL14398190 | 0.79 | DHODH (0.51) | DHODHJAK2THRB | |
| SCHEMBL8150090 | 0.74 | JAK2 (0.53) | DHODHJAK2THRB | |
| SCHEMBL8141776 | 0.73 | JAK2 (0.52) | DHODHJAK2THRB | |
| SCHEMBL15375288 | 0.72 | TYMP (0.62) | TYMP | |
| SCHEMBL648709 | 0.71 | TYMP (0.67) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052341-B1 | OROTIC ACID DERIVATIVES AND THEIR USE AS AGRICULTURAL CHEMICALS | UBE INDUSTRIES, LTD. (JP) | 1985-05-29 | — | — | EP | disclosed |
| US-4400508-A | AGRICULTURE; PLANT DISEASES; ANTISEPTICS | UBE INDUSTRIES, LTD. (JP) | 1983-08-23 | — | — | US | disclosed |
| EP-0052341-A1 | Orotic acid derivatives and their use as agricultural chemicals | UBE INDUSTRIES, LTD. (JP) | 1982-05-26 | — | — | EP | disclosed |