Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 11/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | DPYD | Q12882 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021291 | 0.81 | MCL1 (0.45) | ALDH1A1MCL1KDM4EHPGDPIK3CD | |
| SCHEMBL11018525 | 0.80 | GSK3B (0.45) | ALDH1A1MCL1KDM4EHPGDPIK3CD | |
| SCHEMBL11024880 | 0.79 | MCL1 (0.43) | ALDH1A1MCL1KDM4EHPGDPIK3CD | |
| SCHEMBL11020538 | 0.77 | MCL1 (0.39) | ALDH1A1MCL1KDM4EHPGDPIK3CD | |
| SCHEMBL11023577 | 0.77 | MCL1 (0.39) | ALDH1A1MCL1KDM4EHPGDPIK3CD | |
| Lithium Ion SCHEMBL23214834 | 0.73 | MCL1 (0.46) | ALDH1A1MCL1KDM4EHPGDPIK3CD | |
| SCHEMBL11023093 | 0.72 | KMT2A (0.45) | ALDH1A1MAPTMCL1KDM4EHPGD | |
| SCHEMBL11023237 | 0.71 | KDM4E (0.45) | ALDH1A1MAPTKDM4EHPGDDPYD | |
| SCHEMBL1981825 | 0.71 | POLB (0.48) | ALDH1A1MAPTMCL1KDM4EHPGD | |
| SCHEMBL22542501 | 0.71 | KDM4E (0.48) | ALDH1A1MAPTMCL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |