Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.65 |
| ▸ | ANPEP | P15144 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017147 | 0.87 | DPP4 (0.53) | DPP4ANPEPLMNAGAANPC1 | |
| SCHEMBL11020664 | 0.86 | ANPEP (0.52) | DPP4ANPEPTP53HTTMAPK1 | |
| SCHEMBL11018033 | 0.85 | DPP4 (0.58) | DPP4ANPEPNR1H2NR1H3KMT2A | |
| SCHEMBL11017926 | 0.83 | DPP4 (0.64) | DPP4ANPEPNR1H2NR1H3MAPT | |
| SCHEMBL11021461 | 0.83 | DPP4 (0.64) | DPP4ANPEPNR1H2NR1H3ALDH1A1 | |
| SCHEMBL11018545 | 0.82 | DPP4 (0.57) | DPP4ANPEPHTTNR1H2NR1H3 | |
| SCHEMBL11017368 | 0.82 | DPP4 (0.62) | DPP4ANPEPLMNANR1H2NR1H3 | |
| SCHEMBL11019780 | 0.82 | DPP4 (0.62) | DPP4ANPEPNR1H2NR1H3KMT2A | |
| SCHEMBL11020138 | 0.81 | DPP4 (0.56) | DPP4ANPEPLMNANPC1HTT | |
| SCHEMBL11016999 | 0.81 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |