Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025377 | 0.82 | MCL1 (0.50) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL11017001 | 0.82 | KDM4E (0.50) | PIM1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11026081 | 0.82 | PARP1 (0.50) | PIM1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL11023115 | 0.79 | PDE3B (0.50) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL1162742 | 0.79 | PIM1 (0.54) | PIM1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11020943 | 0.77 | PIM1 (0.42) | PIM1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11019014 | 0.76 | HTT (0.49) | PIM1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL22283897 | 0.75 | ADORA1 (0.51) | PIM1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11023464 | 0.74 | KDM4E (0.46) | PIM1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5504712 | 0.73 | HPGD (0.52) | MAPTKDM4EMEN1KMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |