Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.55 |
| ▸ | ANPEP | P15144 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018073 | 0.86 | DPP4 (0.60) | DPP4ANPEPCYP3A4NR1H2NR1H3 | |
| SCHEMBL11019207 | 0.85 | DPP4 (0.58) | DPP4ANPEPNR1H2NR1H3ALDH1A1 | |
| SCHEMBL11021398 | 0.84 | DPP4 (0.57) | DPP4ANPEPCYP3A4NR1H2NR1H3 | |
| SCHEMBL11018520 | 0.84 | DPP4 (0.57) | DPP4ANPEPNR1H2NR1H3NPSR1 | |
| SCHEMBL11017174 | 0.83 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3TSHR | |
| SCHEMBL11021646 | 0.83 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3TSHR | |
| SCHEMBL11020289 | 0.83 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3NPSR1 | |
| SCHEMBL11020066 | 0.83 | DPP4 (0.64) | DPP4ANPEPNR1H2NR1H3TSHR | |
| SCHEMBL11018718 | 0.83 | DPP4 (0.55) | DPP4ANPEPCYP3A4NR1H2NR1H3 | |
| SCHEMBL11019255 | 0.83 | DPP4 (0.55) | DPP4ANPEPNR1H2NR1H3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |