Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019422 | 0.90 | CYP11B1 (0.61) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL11020035 | 0.88 | CYP11B1 (0.49) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL11023274 | 0.88 | CYP11B1 (0.49) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL9201200 | 0.85 | CYP11B1 (0.56) | CYP19A1CYP11B1CYP11B2KMT2ACYP2A6 | |
| SCHEMBL11020706 | 0.84 | AHR (0.51) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL11020504 | 0.80 | CYP11B1 (0.42) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL11020545 | 0.79 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL9202987 | 0.78 | CYP11B1 (0.48) | CYP19A1CYP11B1CYP11B2KMT2ACYP2A6 | |
| SCHEMBL10505778 | 0.77 | CYP11B1 (0.56) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL11019978 | 0.77 | CYP11B1 (0.42) | CYP19A1CYP11B1CYP11B2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149115-A2 | Derivatives of 2-(1-imidazolyl)-ethanol | BOEHRINGER INGELHEIM KG (DE) | 1985-07-24 | — | — | EP | claimed |
| EP-0149115-A2 | Derivatives of 2-(1-imidazolyl)-ethanol | BOEHRINGER INGELHEIM KG (DE) | 1985-07-24 | — | — | EP | disclosed |