Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 10/20 | 0.43 |
| ▸ | HTR2C | P28335 | 7/20 | 0.43 |
| ▸ | HTR2B | P41595 | 6/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10857223 | 0.97 | HTR2A (0.44) | SMN1; SMN2HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL11018524 | 0.86 | HTR2A (0.44) | HTR2AHTR2CHTR2BHRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL10857042 | 0.85 | KCNH2 (0.44) | HTR2AHTR2CHTR2BHRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL10857036 | 0.85 | KCNH2 (0.44) | HTR2AHTR2CHTR2BHRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL10850138 | 0.83 | HTR2A (0.44) | HTR2AHTR2CHTR2BHRH3KCNH2 | |
| SCHEMBL11016226 | 0.82 | HTR2A (0.40) | HTR2AHTR2CHTR2BHRH3HRH1 | |
| SCHEMBL11018044 | 0.82 | KCNH2 (0.34) | HTR2AKCNH2HRH1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL10855338 | 0.81 | SRD5A2 (0.38) | HTR2AKCNH2HRH1MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL10855971 | 0.81 | KCNH2 (0.34) | HTR2AKCNH2HRH1SLC6A4NPC1 | |
| Hydrochloric Acid SCHEMBL10856997 | 0.81 | KCNH2 (0.34) | HTR2AKCNH2HRH1SLC6A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0139296-A2 | Dihydroisoquinoline derivatives | BEECHAM GROUP PLC (GB) | 1985-05-02 | — | — | EP | claimed |