Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.63 |
| ▸ | ANPEP | P15144 | 3/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021201 | 0.91 | DPP4 (0.59) | DPP4ANPEPCRHBPCRHR2POLB | |
| SCHEMBL11017209 | 0.90 | DPP4 (0.63) | DPP4ANPEPCRHBPCRHR2POLB | |
| SCHEMBL11018014 | 0.89 | DPP4 (0.56) | DPP4ANPEPCRHBPCRHR2POLB | |
| SCHEMBL11020126 | 0.89 | ANPEP (0.56) | DPP4ANPEPCRHBPCRHR2POLB | |
| SCHEMBL11021799 | 0.89 | POLB (0.57) | DPP4ANPEPCRHBPCRHR2POLB | |
| SCHEMBL11018541 | 0.88 | ANPEP (0.55) | DPP4ANPEPBRD4ALDH1A1KMT2A | |
| SCHEMBL11017755 | 0.86 | DPP4 (0.62) | DPP4ANPEPCRHBPCRHR2TYMS | |
| SCHEMBL11018587 | 0.85 | ANPEP (0.52) | DPP4ANPEPPOLBALDH1A1KMT2A | |
| SCHEMBL11022146 | 0.85 | DPP4 (0.68) | DPP4ANPEPCRHBPCRHR2POLB | |
| SCHEMBL11022176 | 0.84 | DPP4 (0.63) | DPP4ANPEPCRHBPCRHR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |