Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1092212 | 0.79 | MPL (0.67) | MPL | |
| SCHEMBL1091675 | 0.78 | MPL (0.70) | MPL | |
| SCHEMBL1102156 | 0.78 | MPL (1.00) | MPL | |
| SCHEMBL1091149 | 0.76 | MPL (0.69) | MPL | |
| SCHEMBL1102278 | 0.75 | MPL (0.73) | MPL | |
| SCHEMBL1090937 | 0.75 | MPL (0.73) | MPL | |
| SCHEMBL1091553 | 0.73 | MPL (0.77) | MPL | |
| SCHEMBL1092251 | 0.73 | MPL (0.71) | MPL | |
| SCHEMBL1091360 | 0.73 | MPL (0.90) | MPL | |
| SCHEMBL1091661 | 0.70 | MPL (0.67) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153671-B2 | Heterotetracyclic compounds as TPO mimetics | IRM LLC (BM) | 2012-04-10 | — | — | US | disclosed |