Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873130 | 0.89 | IDO1 (0.68) | IDO1NPC1CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL865549 | 0.89 | IDO1 (0.68) | IDO1NPC1CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL13518899 | 0.81 | IDO1 (0.59) | IDO1NPC1CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL1109862 | 0.81 | IDO1 (0.59) | IDO1NPC1CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL7228371 | 0.80 | IDO1 (0.53) | IDO1NPC1CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL6236937 | 0.79 | IDO1 (0.57) | IDO1NPC1CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL14947971 | 0.78 | TSHR (0.48) | IDO1ALDH1A1RAB9ATSHRNPSR1 | |
| SCHEMBL12885103 | 0.78 | IDO1 (0.55) | IDO1NPC1CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL10458219 | 0.78 | IDO1 (0.55) | IDO1NPC1CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL1179916 | 0.78 | IDO1 (0.55) | IDO1NPC1CYP2D6ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160573-A2 | Pyrimidinone derivatives | NYCOMED AS (NO) | 1985-11-06 | — | — | EP | disclosed |