Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 17/20 | 0.62 |
| ▸ | CACNA1D | Q01668 | 17/20 | 0.62 |
| ▸ | CACNA1S | Q13698 | 17/20 | 0.62 |
| ▸ | CACNA1C | Q13936 | 17/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022662 | 0.92 | CACNA1C (0.57) | CACNA1FCACNA1DCACNA1SCACNA1CHIF1A | |
| SCHEMBL11018577 | 0.91 | CACNA1F (0.59) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11019962 | 0.91 | CACNA1F (0.61) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11022578 | 0.91 | CACNA1F (0.61) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11052829 | 0.91 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11021693 | 0.91 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11018691 | 0.90 | CACNA1C (0.59) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11020568 | 0.90 | CACNA1F (0.59) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| Hydrochloric Acid SCHEMBL11020440 | 0.89 | CACNA1C (0.58) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11019531 | 0.88 | CACNA1F (0.64) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163240-A2 | Dihydroimidazo[1,2-a]pyrimidine derivatives, methods of preparing said compounds and pharmaceutical compositions constaining said compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-12-04 | — | — | EP | disclosed |