Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24454854 | 1.00 | — | — | |
| SCHEMBL407168 | 1.00 | SMN1; SMN2 (0.31) | SMN1; SMN2CHRNA7DUSP3PTPN5PTPN11 | |
| SCHEMBL27631046 | 0.96 | — | — | |
| SCHEMBL4450796 | 0.96 | TSHR (0.30) | — | |
| Dimethylamine SCHEMBL8371583 | 0.89 | KDM4E (0.30) | — | |
| SCHEMBL5493927 | 0.86 | MAPT (0.30) | — | |
| SCHEMBL575183 | 0.84 | — | — | |
| Diethylamine SCHEMBL9478387 | 0.83 | TP53 (0.50) | CYP1A2CYP2C19 | |
| SCHEMBL12669729 | 0.81 | — | — | |
| Bromide SCHEMBL5145721 | 0.81 | CHRNA7 (0.37) | SMN1; SMN2CHRNA7DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153784-B2 | Imaging of enzyme activity | THE GENERAL HOSPITAL CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-20080044827-A1 | Imaging of Enzyme Activity | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080044827-A1 | Imaging of Enzyme Activity | GBA3, BCHE, MGAM | SMN1; SMN2 828/4885CHRNA7 2023/4885DUSP3 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.