Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16552798 | 0.89 | NR5A1 (0.58) | CYP3A4CYP2D6CYP1A2NR5A1RARB | |
| SCHEMBL13309870 | 0.89 | NR5A1 (0.58) | CYP3A4CYP2D6CYP1A2NR5A1RARB | |
| SCHEMBL3791496 | 0.87 | NR5A1 (0.56) | CYP3A4CYP2D6CYP1A2NR5A1RARB | |
| SCHEMBL2396650 | 0.87 | NR5A1 (0.56) | CYP3A4CYP2D6CYP1A2NR5A1RARB | |
| SCHEMBL16552630 | 0.87 | CYP2D6 (0.58) | CYP3A4CYP2D6CYP1A2NR5A1RARB | |
| SCHEMBL16558130 | 0.83 | NR5A1 (0.51) | CYP3A4CYP2D6CYP1A2NR5A1RARB | |
| SCHEMBL16558135 | 0.83 | NR5A1 (0.51) | CYP3A4CYP2D6CYP1A2NR5A1RARB | |
| SCHEMBL14182498 | 0.82 | CYP3A4 (0.40) | CYP3A4CYP2D6CYP1A2NR5A1RARB | |
| SCHEMBL16558134 | 0.81 | CYP3A4 (0.53) | CYP3A4CYP2D6CYP1A2NR5A1RARB | |
| SCHEMBL8984070 | 0.81 | CYP3A4 (0.56) | CYP3A4CYP2D6CYP1A2NR5A1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153822-B2 | Fluorene compound | FUJI XEROX CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20100197942-A1 | NOVEL FLUORENE COMPOUND | FUJI XEROX CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197942-A1 | NOVEL FLUORENE COMPOUND | AFF1, AFF2, FLI1 | CYP3A4 1108/4885CYP2D6 1338/4885CYP1A2 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.