Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193044 | 1.00 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 | |
| SCHEMBL11024795 | 1.00 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 | |
| SCHEMBL10966539 | 1.00 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 | |
| SCHEMBL11351044 | 1.00 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 | |
| SCHEMBL10966310 | 1.00 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 | |
| SCHEMBL10968227 | 0.97 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 | |
| Oxalic Acid SCHEMBL10965391 | 0.94 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 | |
| Oxalic Acid SCHEMBL10965384 | 0.94 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 | |
| SCHEMBL11051769 | 0.86 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 | |
| SCHEMBL10965845 | 0.86 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3OPRM1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061899-B1 | MORPHOLINES | JOHN WYETH & BROTHER LIMITED (GB) | 1985-03-20 | — | — | EP | disclosed |