SCHEMBL1102470

SCHEMBL1102470

CC(C)c1cccc(-c2c3ccccc3c(-c3ccccc3)c3ccncc23)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.40
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
TNF P01375 1/20 0.39
DGAT2 Q96PD7 1/20 0.37
FABP3 P05413 1/20 0.37
CYP2C9 P11712 1/20 0.37
FABP4 P15090 1/20 0.37
FABP5 Q01469 1/20 0.37
LATS1 O95835 1/20 0.36
METAP2 P50579 1/20 0.36
PTPN5 P54829 2/20 0.35
ALOX5 P09917 1/20 0.35
KDR P35968 1/20 0.35
CLK1 P49759 1/20 0.35
DYRK1A Q13627 1/20 0.35
MAP2 P11137 1/20 0.35
CNR1 P21554 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1102468 0.89 CYP17A1 (0.46) IDO1RXRARXRBRXRGTNF
SCHEMBL1102537 0.87 TNF (0.46) IDO1TNFKDRKDM4E
SCHEMBL1102450 0.87 MAPK13 (0.44) TNFDGAT2LATS1METAP2KDR
SCHEMBL1102455 0.87 CYP17A1 (0.42) TNFDGAT2MAPK10
SCHEMBL1102519 0.85 MAPK13 (0.43) TNFDGAT2LATS1KDRMAP2
SCHEMBL1102701 0.85 TNF (0.47) IDO1TNFALOX5MAP2KDM4E
SCHEMBL1102927 0.85 TNF (0.47) IDO1TNFALOX5MAP2KDM4E
SCHEMBL1102555 0.82 TNF (0.45) IDO1TNFALOX5MAP2KDM4E
SCHEMBL1102490 0.81 TNF (0.48) IDO1TNFALOX5MAP2KDM4E
SCHEMBL1102617 0.81 RPS6KA3 (0.42) TNFCNR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 IDO1 1871/4885RXRA 2293/4885RXRB 2304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.