Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024657 | 0.81 | TSHR (0.50) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL5272432 | 0.80 | TSHR (0.41) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL5277829 | 0.77 | PPARD (0.47) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL11047025 | 0.77 | TSHR (0.54) | TSHRPPARDCA12CA1CA2 | |
| Carbamic Acid SCHEMBL28214317 | 0.77 | TSHR (0.71) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL11045332 | 0.74 | TSHR (0.42) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL9844531 | 0.72 | TSHR (0.62) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL11741097 | 0.72 | TSHR (0.62) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL26483 | 0.72 | TSHR (1.00) | TSHRPPARD | |
| SCHEMBL5961215 | 0.72 | TSHR (1.00) | TSHRPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063411-B1 | SUBSTITUTED METHANEPHOSHONIC ACID DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR PREPARING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-05 | — | — | EP | disclosed |
| EP-0063411-A1 | Substituted methanephoshonic acid derivatives, their use as herbicides, herbicidal compositions containing them, and processes for preparing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-10-27 | — | — | EP | disclosed |