Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2677587 | 0.94 | POLB (0.90) | POLBSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL11761148 | 0.92 | POLB (0.84) | POLBSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL28134814 | 0.90 | POLB (0.81) | POLBSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL8654966 | 0.90 | POLB (0.81) | POLBSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL1233409 | 0.89 | POLB (0.81) | POLBSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL3199273 | 0.89 | POLB (0.80) | POLBSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL1232924 | 0.87 | POLB (0.77) | POLBHPGD | |
| SCHEMBL28907470 | 0.86 | POLB (0.76) | POLBSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL3880413 | 0.86 | POLB (0.76) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL21523581 | 0.86 | POLB (0.76) | POLBSMN1; SMN2MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059108-B1 | DERIVATIVES OF DIHYDROXYBENZOIC ACID | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-08-14 | — | — | EP | disclosed |
| US-4409240-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS, BRONCHODILATOR, AND ANTIARTHRITIC AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0059108-A1 | Derivatives of dihydroxybenzoic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-09-01 | — | — | EP | disclosed |