Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025502 | 1.00 | TSHR (0.41) | TSHRAKT1LMNAALDH1A1MGAM | |
| SCHEMBL28818420 | 0.80 | TSHR (0.37) | TSHRLMNAUSP2CYP3A4MAPT | |
| SCHEMBL28847936 | 0.79 | TSHR (0.39) | TSHRLMNAUSP2CYP3A4MAPT | |
| SCHEMBL10699354 | 0.79 | TSHR (0.39) | TSHRLMNAUSP2CYP3A4MAPT | |
| SCHEMBL10699348 | 0.79 | TSHR (0.39) | TSHRLMNAUSP2CYP3A4MAPT | |
| SCHEMBL29860909 | 0.78 | TSHR (0.55) | TSHRLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11024070 | 0.77 | TSHR (0.35) | TSHRAKT1ALDH1A1MGAMGAA | |
| SCHEMBL11024067 | 0.77 | TSHR (0.35) | TSHRAKT1ALDH1A1MGAMGAA | |
| SCHEMBL11149144 | 0.76 | USP2 (0.41) | TSHRLMNAUSP2CYP3A4MAPT | |
| SCHEMBL11149146 | 0.76 | USP2 (0.41) | TSHRLMNAUSP2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529814-A | Acyloxyalkadienoates and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1985-07-16 | — | — | US | disclosed |