⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029372 | 0.72 | — | — | |
| SCHEMBL17811631 | 0.69 | — | — | |
| SCHEMBL31040521 | 0.67 | — | — | |
| SCHEMBL28789093 | 0.65 | — | — | |
| SCHEMBL2272310 | 0.64 | — | — | |
| SCHEMBL8275487 | 0.64 | — | — | |
| SCHEMBL172298 | 0.62 | — | — | |
| SCHEMBL31230878 | 0.62 | — | — | |
| SCHEMBL7041012 | 0.62 | — | — | |
| SCHEMBL31532320 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424158-A | HALOMETHYLTRIALKYLSILANE, MAGNESIUM, DIPHENYLPHORPHORIC AZIDE | CHISSO CORPORATION (JP) | 1984-01-03 | — | — | US | claimed |
| EP-0071440-B1 | PROCESS FOR PREPARING TRIALKYLSILYLDIAZOMETHANES | Chisso Corporation (JP) | 1985-05-02 | — | — | EP | disclosed |
| US-4424158-A | HALOMETHYLTRIALKYLSILANE, MAGNESIUM, DIPHENYLPHORPHORIC AZIDE | CHISSO CORPORATION (JP) | 1984-01-03 | — | — | US | disclosed |