Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028402 | 0.99 | SPHK1 (0.40) | SPHK1CYP2C9MAPTCNR2GAA | |
| SCHEMBL6459972 | 0.96 | MAPT (0.36) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL6459966 | 0.96 | MAPT (0.36) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL6454027 | 0.95 | SPHK1 (0.37) | SPHK1CYP2C9MAPTCNR2GAA | |
| SCHEMBL6454024 | 0.95 | SPHK1 (0.37) | SPHK1CYP2C9MAPTCNR2GAA | |
| SCHEMBL6454257 | 0.95 | SPHK1 (0.37) | SPHK1CYP2C9MAPTCNR2GAA | |
| SCHEMBL6454252 | 0.95 | SPHK1 (0.37) | SPHK1CYP2C9MAPTCNR2GAA | |
| SCHEMBL6453358 | 0.92 | FFAR1 (0.39) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL6453364 | 0.92 | FFAR1 (0.39) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL6464367 | 0.92 | CYP2C9 (0.35) | SPHK1CYP2C9MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432885-A | Decalins | HOFFMANN-LA ROCHE INC. (US) | 1984-02-21 | — | — | US | disclosed |