SCHEMBL1102834

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1102812	0.91	TNF (0.47)	TNFKDRMAPK14RAB9AKDM4E
	SCHEMBL1102523	0.89	RPS6KA3 (0.43)	TNFKDRMAPK14ENPP1RAB9A
	SCHEMBL1105444	0.89	TNF (0.43)	TNFKDRMAPK14RAB9AKDM4E
	SCHEMBL1102801	0.88	TNF (0.56)	TNFMAPK14RAB9AKDM4EALDH1A1
	SCHEMBL1102796	0.88	TNF (0.56)	TNFMAPK14RAB9AKDM4EALDH1A1
	SCHEMBL1102956	0.88	TNF (0.56)	TNFMAPK14RAB9AKDM4EALDH1A1
	SCHEMBL1102976	0.86	TNF (0.48)	TNFKDRMAPK14ENPP1RAB9A
	SCHEMBL1102791	0.86	TNF (0.55)	TNFMAPK14RAB9AKDM4EALDH1A1
	SCHEMBL1103614	0.86	KDR (0.45)	TNFKDRMAPK14KDM4EALDH1A1
	SCHEMBL1102617	0.86	RPS6KA3 (0.42)	TNFMAPK14RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.