Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.62 |
| ▸ | GAA | P10253 | 6/20 | 0.62 |
| ▸ | GLA | P06280 | 5/20 | 0.62 |
| ▸ | CASP1 | P29466 | 5/20 | 0.62 |
| ▸ | CASP7 | P55210 | 5/20 | 0.62 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.54 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580428 | 0.91 | ATM (1.00) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17717500 | 0.91 | ATM (1.00) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14561715 | 0.81 | ATM (0.64) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5234524 | 0.81 | ATM (0.64) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5234530 | 0.81 | ATM (0.64) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5229367 | 0.81 | ATM (0.64) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8802453 | 0.76 | ATM (0.51) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5229574 | 0.76 | ATM (0.58) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5229562 | 0.76 | ATM (0.58) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5229567 | 0.76 | ATM (0.58) | ATMKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127634-A1 | PYRROLOCOUMARIN DERIVATIVES, THEIR MANUFACTURE AND UTILISATION | KATHOLIEKE UNIVERSITEIT TE LEUVEN (BE) | 1984-12-12 | — | — | EP | disclosed |
| WO-1984002133-A1 | PYRROLOCOUMARIN DERIVATIVES, THEIR MANUFACTURE AND UTILISATION | UNIV LEUVEN KATH (BE) | 1984-06-07 | — | — | WO | disclosed |