Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783030 | 1.00 | CYSLTR1 (0.45) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 | |
| SCHEMBL1551300 | 1.00 | CYSLTR1 (0.45) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 | |
| SCHEMBL28194971 | 1.00 | CYSLTR1 (0.45) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 | |
| SCHEMBL9186483 | 1.00 | CYSLTR1 (0.45) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 | |
| SCHEMBL1551574 | 1.00 | CYSLTR1 (0.45) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 | |
| SCHEMBL12603937 | 1.00 | CYSLTR1 (0.45) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 | |
| SCHEMBL12603960 | 1.00 | CYSLTR1 (0.45) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 | |
| SCHEMBL9598037 | 0.98 | CYSLTR1 (0.46) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 | |
| SCHEMBL898777 | 0.93 | PDE10A (0.47) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 | |
| Hydrochloric Acid SCHEMBL29127709 | 0.91 | PDE10A (0.46) | CYSLTR1PDE10ACYP1A2CYSLTR2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981525-A1 | MULTIFUNCTIONAL QUINOLINE DERIVATIVES AS ANTI-NEURODEGENERATIVE AGENTS | Annji Pharmaceutical Co., Ltd. (CN) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014163622-A1 | MULTIFUNCTIONAL QUINOLINE DERIVATIVES AS ANTI-NEURODEGENERATIVE AGENTS | Annji Pharmaceutical Co., Ltd. (CN) | 2014-10-09 | — | — | WO | disclosed |
| US-4446279-A | Compositions based on a polysiloxane and an organo titanate and the use thereof in the preparation of water curable, silane modified alkylene-alkyl acrylate copolymers | UNION CARBIDE CORPORATION (US) | 1984-05-01 | — | — | US | disclosed |