Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KDM5C | P41229 | 1/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.54 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24657787 | 0.98 | HSP90AA1 (0.61) | HSP90AA1FAAHKDM4EKDM5CEGLN1 | |
| SCHEMBL13568685 | 0.98 | HSP90AA1 (0.61) | HSP90AA1FAAHKDM4EKDM5CEGLN1 | |
| SCHEMBL29040279 | 0.98 | HSP90AA1 (0.61) | HSP90AA1FAAHKDM4EKDM5CEGLN1 | |
| SCHEMBL24658011 | 0.98 | HSP90AA1 (0.61) | HSP90AA1FAAHKDM4EKDM5CEGLN1 | |
| SCHEMBL11027904 | 0.93 | — | — | |
| SCHEMBL6124941 | 0.90 | KDM4E (0.64) | HSP90AA1FAAHKDM4EKDM5CEGLN1 | |
| SCHEMBL29379925 | 0.87 | HSP90AA1 (0.65) | HSP90AA1FAAHKDM4EKMT2AMAPT | |
| SCHEMBL6470717 | 0.85 | HSP90AA1 (0.70) | HSP90AA1FAAHKDM4EKMT2AMAPT | |
| SCHEMBL22960696 | 0.85 | HSP90AA1 (0.70) | HSP90AA1FAAHKDM4EKMT2AMAPT | |
| SCHEMBL7108790 | 0.85 | HSP90AA1 (0.70) | HSP90AA1FAAHKDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126088-A1 | ARYL SUBSTITUTED 7-OXABICYCLOHEPTANE COMPOUNDS | E.R. SQUIBB & SONS, INC. (US) | 1984-11-28 | — | — | EP | disclosed |
| US-4463015-A | Aryl substituted 7-oxabicycloheptane compounds, useful in inhibiting platelet aggregation | E. R. SQUIBB & SONS, INC. (US) | 1984-07-31 | — | — | US | disclosed |
| WO-1984000754-A1 | ARYL SUBSTITUTED 7-OXABICYCLOHEPTANE COMPOUNDS | SQUIBB & SONS INC (US) | 1984-03-01 | — | — | WO | disclosed |
| US-4418076-A | 7-Oxabicycloheptane hydrazone prostaglandin analogs useful in treating thrombolytic diseases | E. R. SQUIBB & SONS, INC. (US) | 1983-11-29 | — | — | US | disclosed |