⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964682 | 0.93 | KCNH2 (0.35) | — | |
| SCHEMBL10963694 | 0.93 | KCNH2 (0.35) | — | |
| SCHEMBL10964530 | 0.93 | KCNH2 (0.35) | — | |
| SCHEMBL10960835 | 0.93 | KCNH2 (0.35) | — | |
| SCHEMBL10962416 | 0.93 | KCNH2 (0.35) | — | |
| SCHEMBL10962438 | 0.93 | KCNH2 (0.35) | — | |
| SCHEMBL10961893 | 0.93 | KCNH2 (0.35) | — | |
| SCHEMBL10962753 | 0.93 | KCNH2 (0.35) | — | |
| SCHEMBL9255700 | 0.93 | KCNH2 (0.35) | — | |
| SCHEMBL10965254 | 0.93 | KCNH2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31587-E | Process for the preparation of 3-iminomethyl derivatives of rifamycin SV | ARCHIFAR LABORATORI CHIMICO FARMACOLOGICI S.P.A. (IT) | 1984-05-22 | — | — | US | disclosed |
| US-3963705-A | Process for the preparation of 3-iminomethyl derivatives of rifamycin SV | ARCHIFAR INDUSTRIE CHIMICHE DEL TRENTINO S.P.A. (IT) | 1976-06-15 | — | — | US | disclosed |