⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL28249972 | 1.00 | TSHR (0.82) | — | |
| Dimethylformamide SCHEMBL11046253 | 0.96 | TSHR (0.75) | — | |
| Dimethylformamide SCHEMBL8336134 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL10141201 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL2280000 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL1332179 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL5 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL1927321 | 0.91 | TSHR (1.00) | — | |
| Dimethylformamide SCHEMBL22749119 | 0.86 | — | — | |
| Dimethylformamide SCHEMBL11130163 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200317660-A1 | Quinazolinone Compound and Application Thereof | Luoxin Healthcare Science and Technology Development (Beijing) Ltd. (CN) | 2020-10-08 | — | — | US | disclosed |
| EP-3712143-A1 | QUINAZOLINONE COMPOUND AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |
| CN-104650372-B | A kind of thermosetting polymer composite, poly- half amide supermolecular film and preparation method | 华南理工大学 | 2017-10-20 | — | — | CN | disclosed |
| CN-1293056-C | 4-phenyl-pyridine derivatives as neurokinin-1 receptor antagonists | HOFFMANN LA ROCHE (CH) | 2007-01-03 | — | — | CN | disclosed |
| CN-1610670-A | 4-phenyl-pyridine derivatives as neurokinin-1 receptor antagonists | HOFFMANN LA ROCHE (CH) | 2005-04-27 | — | — | CN | disclosed |
| US-4536391-A | REACTING A PLASMIN HEAVY CHAIN WITH UROKINASE IN THE PRESENCE OF A COUPLING AGENT | OTSUKA PHARMACEUTICAL CO. (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0123927-A2 | Water resistant compositions | KURARAY CO., LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |