Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789531 | 0.94 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL31405830 | 0.91 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL8505774 | 0.91 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL8565036 | 0.90 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL185499 | 0.90 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4FAAH | |
| SCHEMBL28057272 | 0.89 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL6731836 | 0.89 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Ethylene SCHEMBL28845826 | 0.89 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4FAAH | |
| SCHEMBL29143535 | 0.89 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4FAAH | |
| SCHEMBL31636154 | 0.87 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4521549-A | POLYMER COMPOUND, ALUMINA HYDRATE, OXIDE | RAYCHEM CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |
| US-4399064-A | ALUMINA, METAL OXIDE FILLERS | RAYCHEM CORPORATION (US) | 1983-08-16 | — | — | US | disclosed |
| US-4223071-A | ANTITRACKING ADDITIVES, RESISTANCE TO HIGH VOLTAGE ERROSION | RAYCHEM CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4219607-A | High voltage insulating compositions containing phosphorus compounds | RAYCHEM CORPORATION (US) | 1980-08-26 | — | — | US | disclosed |
| US-4198310-A | High voltage insulating compositions containing organic polymerizable phosphorus compounds | RAYCHEM CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4100089-A | High-voltage insulating material comprising anti-tracking and erosion inhibiting compounds with insulating polymers | RAYCHEM CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |