SCHEMBL11032178

SCHEMBL11032178

C=CCC(=C)C(=O)C1=CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 3/20 0.43
HDAC4 P56524 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
CTSK P43235 1/20 0.40
HDAC3 O15379 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
CCR2 P41597 1/20 0.34
GSTP1 P09211 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3629657 0.85 HDAC2 (0.44) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL323973 0.81 HDAC2 (0.47) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL11057595 0.80 HDAC2 (0.43) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL2702713 0.79 HDAC4 (0.40) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL28244702 0.75 HDAC4 (0.46) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL3629130 0.75 HDAC2 (0.48) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL3628786 0.74 HDAC4 (0.41) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL4635958 0.73 HDAC2 (0.50) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL4022755 0.72 HDAC2 (0.53) HDAC2HDAC4HDAC8HDAC6CTSK
Hydrochloric Acid SCHEMBL10623276 0.72 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4492645-A Organoleptic use of cyclohexenyl-alpha-alkyl acrolein derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-01-08 US disclosed
US-4492645-A Organoleptic use of cyclohexenyl-alpha-alkyl acrolein derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-01-08 US disclosed
US-4492645-A Organoleptic use of cyclohexenyl-alpha-alkyl acrolein derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-01-08 US disclosed
US-4487701-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-12-11 US disclosed
US-4487701-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-12-11 US disclosed
US-4487701-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-12-11 US disclosed
US-4480647-A Use of cyclohexenyl-alkyl acrolein derivatives in augmenting or enhancing the aroma or taste of smoking tobacco compositions and smoking tobacco articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-11-06 US disclosed
US-4480647-A Use of cyclohexenyl-alkyl acrolein derivatives in augmenting or enhancing the aroma or taste of smoking tobacco compositions and smoking tobacco articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-11-06 US disclosed
US-4427708-A Use of cyclohexenyl-alpha-alkyl acrolein derivatives in augmenting or enhancing the aroma or taste of foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-01-24 US disclosed
US-4427708-A Use of cyclohexenyl-alpha-alkyl acrolein derivatives in augmenting or enhancing the aroma or taste of foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-01-24 US disclosed
US-4427708-A Use of cyclohexenyl-alpha-alkyl acrolein derivatives in augmenting or enhancing the aroma or taste of foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-01-24 US disclosed
US-4424379-A FLAVORS, TASTES, ODORS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-01-03 US disclosed
US-4424379-A FLAVORS, TASTES, ODORS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-01-03 US disclosed
US-4424379-A FLAVORS, TASTES, ODORS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-01-03 US disclosed