Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940035 | 1.00 | CYP19A1 (0.48) | CYP19A1MAPK1KMT2AHSP90AA1CYP3A4 | |
| Flusilazole SCHEMBL8677611 | 0.94 | CYP19A1 (0.49) | CYP19A1MAPK1KMT2AHSP90AA1CYP3A4 | |
| Flusilazole SCHEMBL7049517 | 0.94 | CYP19A1 (0.49) | CYP19A1MAPK1KMT2AHSP90AA1CYP3A4 | |
| Flusilazole SCHEMBL21313 | 0.94 | CYP19A1 (0.49) | CYP19A1MAPK1KMT2AHSP90AA1CYP3A4 | |
| SCHEMBL10946336 | 0.91 | CYP19A1 (0.53) | CYP19A1KMT2AHSP90AA1LMNAHTT | |
| SCHEMBL17018813 | 0.88 | CYP19A1 (0.44) | CYP19A1MAPK1KMT2AHSP90AA1CYP3A4 | |
| SCHEMBL11031755 | 0.87 | MAPT (0.49) | CYP19A1KMT2AHSP90AA1LMNAHTT | |
| Flusilazole SCHEMBL9677988 | 0.85 | CYP19A1 (0.39) | CYP19A1MAPK1KMT2AHSP90AA1CYP3A4 | |
| SCHEMBL10939860 | 0.85 | CYP19A1 (0.49) | CYP19A1KMT2AHSP90AA1CYP3A4LMNA | |
| SCHEMBL10947085 | 0.85 | CYP19A1 (0.50) | CYP19A1KMT2AHSP90AA1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068813-B1 | FUNGICIDAL 1,2,4-TRIAZOLE AND IMIDAZOLE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-09-25 | — | — | EP | claimed |