Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.58 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | CPA2 | P48052 | 1/20 | 0.51 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503213 | 0.94 | MME (0.55) | MMECPA1CPA2CPA4MMP2 | |
| SCHEMBL11031714 | 0.93 | MME (0.56) | MMECPA1CPA2CPA4ECE1 | |
| SCHEMBL11033973 | 0.92 | MME (0.55) | MMECPA1CPA2CPA4ECE1 | |
| SCHEMBL11032748 | 0.88 | MME (0.60) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL11032754 | 0.87 | MME (0.54) | MMEECE1 | |
| Monoethanolamine SCHEMBL11032722 | 0.87 | MME (0.54) | MMECPA1CPA2CPA4ECE1 | |
| SCHEMBL11032948 | 0.87 | MME (0.54) | MMEECE1 | |
| SCHEMBL11202543 | 0.87 | MME (0.64) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL11031934 | 0.86 | MME (0.53) | MMEECE1 | |
| SCHEMBL9069584 | 0.86 | MME (0.63) | MMEMMP2MMP7MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432972-A | HYPOTENSIVE AGENTS, KANALGESICS, AND ANGIOTENSIN AND ENKEPHALIN INHIBITION | E. R. SQUIBB & SONS, INC. (US) | 1984-02-21 | — | — | US | disclosed |