SCHEMBL11033773

SCHEMBL11033773

CCCCCC[C@H]1CC[C@H](c2ccc(Br)cc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.50
MAPT P10636 2/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
MEN1 O00255 1/20 0.48
MAPK1 P28482 1/20 0.48
KMT2A Q03164 1/20 0.48
SPHK1 Q9NYA1 12/20 0.48
GAA P10253 1/20 0.43
ESR2 Q92731 1/20 0.42
SPHK2 Q9NRA0 7/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10975417 1.00 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10980214 1.00 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL8743735 1.00 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10979927 1.00 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL9073150 1.00 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10979893 1.00 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL11033775 1.00 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10975420 1.00 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL10980217 1.00 CYP2C9 (0.50) CYP2C9MAPTALDH1A1LMNAMEN1
SCHEMBL223135 0.98 CYP2C9 (0.51) CYP2C9MAPTALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0074608-B1 LIQUID CRYSTAL HALOGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION, DIELECTRIC AND DECTROOPTICAL DISPLAY ELEMENT CONTAINING THEM MERCK PATENT GmbH (DE) 1985-07-03 EP disclosed
US-4490305-A Liquid-crystalline halogen compounds, process for their preparation, dielectrics containing these, and electro-optical display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-12-25 US disclosed
EP-0074608-A2 Liquid crystal halogen compounds, process for their preparation, dielectric and dectrooptical display element containing them MERCK PATENT GmbH (DE) 1983-03-23 EP disclosed