Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032301 | 0.92 | MAPT (0.42) | PDE3ANQO1KDM4EALDH1A1MAPT | |
| SCHEMBL11035510 | 0.91 | MAPT (0.47) | PDE3ANQO1KDM4EALDH1A1MAPT | |
| SCHEMBL11031805 | 0.90 | MAPT (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL11035312 | 0.90 | MAPT (0.41) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL11034105 | 0.89 | MAPT (0.46) | PDE3ANQO1KDM4EALDH1A1MAPT | |
| SCHEMBL11033238 | 0.89 | MAPT (0.46) | PDE3ANQO1KDM4EALDH1A1MAPT | |
| SCHEMBL11033414 | 0.89 | MAPT (0.46) | PDE3ANQO1KDM4EALDH1A1MAPT | |
| SCHEMBL11035587 | 0.89 | MAPT (0.46) | PDE3ANQO1KDM4EALDH1A1MAPT | |
| SCHEMBL10581653 | 0.89 | MAPT (0.40) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL10579032 | 0.88 | MAPT (0.45) | PDE3ANQO1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479885-A | Phthalonitrile derivatives and a liquid crystal composition containing the same | HITACHI, LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0087963-A2 | Phthalonitrile derivatives and liquid crystal compositions containing them | Hitachi, Ltd. (JP) | 1983-09-07 | — | — | EP | disclosed |