Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513780 | 0.86 | HSD17B10 (0.61) | HSD17B10USP2HTTCYP1A2CYP3A4 | |
| SCHEMBL8016289 | 0.86 | HSD17B10 (0.61) | HSD17B10USP2HTTCYP1A2CYP3A4 | |
| SCHEMBL8016294 | 0.86 | HSD17B10 (0.61) | HSD17B10USP2HTTCYP1A2CYP3A4 | |
| SCHEMBL28464587 | 0.82 | USP2 (0.55) | HSD17B10USP2HTTCYP1A2CYP3A4 | |
| SCHEMBL4746506 | 0.82 | — | — | |
| SCHEMBL5907150 | 0.81 | KDM4E (0.48) | HSD17B10USP2HTTCYP1A2CYP3A4 | |
| SCHEMBL795575 | 0.80 | USP2 (0.48) | HSD17B10USP2HTTCYP1A2CYP3A4 | |
| SCHEMBL7171054 | 0.80 | USP2 (0.59) | HSD17B10USP2HTTCYP1A2CYP3A4 | |
| SCHEMBL28254598 | 0.79 | USP2 (0.53) | HSD17B10USP2HTTCYP1A2CYP3A4 | |
| SCHEMBL2563382 | 0.78 | USP2 (0.52) | HSD17B10USP2HTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4522824-A | ADRENERGIC BLOCKING AGENTS | SANOFI (FR) | 1985-06-11 | — | — | US | disclosed |