Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042348 | 1.00 | KMT2A (0.58) | KMT2ALMNAMEN1PTPN1PTPN2 | |
| SCHEMBL11042319 | 1.00 | KMT2A (0.58) | KMT2ALMNAMEN1PTPN1PTPN2 | |
| SCHEMBL11270692 | 0.92 | KMT2A (0.55) | KMT2ALMNAMEN1PTPN1PTPN2 | |
| SCHEMBL11041684 | 0.92 | KMT2A (0.55) | KMT2ALMNAMEN1PTPN1PTPN2 | |
| SCHEMBL11041683 | 0.92 | KMT2A (0.55) | KMT2ALMNAMEN1PTPN1PTPN2 | |
| SCHEMBL6696396 | 0.86 | CYP2C9 (0.44) | KMT2ALMNAMEN1PTPN1PTPN2 | |
| SCHEMBL5835906 | 0.86 | CYP2C9 (0.44) | KMT2ALMNAMEN1PTPN1PTPN2 | |
| SCHEMBL6696392 | 0.86 | CYP2C9 (0.44) | KMT2ALMNAMEN1PTPN1PTPN2 | |
| SCHEMBL10799986 | 0.86 | CYP2C9 (0.44) | KMT2ALMNAMEN1PTPN1PTPN2 | |
| SCHEMBL8474335 | 0.85 | MEN1 (0.52) | KMT2ALMNAMEN1CYP2C9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59110653-A | — | — | None | — | — | JP | disclosed |
| JP-S59110653-A | HALOGEN-CONTAINING TERCYCLOHEXANOL DERIVATIVE | CHISSO CORP | 1984-06-26 | — | — | JP | disclosed |