Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.59 |
| ▸ | CYSLTR2 | Q9NS75 | 12/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | PDE5A | O76074 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049754 | 0.90 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 | |
| SCHEMBL10557524 | 0.86 | CYSLTR2 (0.54) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 | |
| SCHEMBL10730826 | 0.85 | GRM2 (0.61) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 | |
| SCHEMBL10958449 | 0.83 | GRM2 (0.63) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 | |
| Acetic Acid SCHEMBL10557517 | 0.82 | CYSLTR2 (0.57) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 | |
| SCHEMBL11056160 | 0.81 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 | |
| SCHEMBL11460103 | 0.81 | CYSLTR2 (0.58) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 | |
| SCHEMBL10479997 | 0.79 | CYSLTR2 (0.54) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 | |
| SCHEMBL11026927 | 0.79 | MAPT (0.57) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 | |
| SCHEMBL10725941 | 0.79 | CYSLTR2 (0.54) | CYSLTR1CYSLTR2MAPTPDE5AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59076038-A | — | — | None | — | — | JP | disclosed |
| JP-S5976038-A | BENZOIC ACID DERIVATIVE, ITS PREPARATION AND DRUG CONTAINING THE SAME | TAKEDA CHEM IND LTD | 1984-04-28 | — | — | JP | disclosed |